Drug Response Link Prediction (DRLP)

About DRLP

DRLP creates a representation of multiple data types as a heterogeneous network that integrates the relationships between drugs, cell lines, molecular aberrations, and functional associations among biomolecules. We compute "network profiles" for drugs and cell lines, which represent their location in this network. The associations between these profiles are then used to predict links between drugs and cell lines, which correspond to cell line sensitivity.

DRLP is implemented in MATLAB. Scripts and required data files can be downloaded from the above tab.