Modularity Based Scoring Subnetwork (MoBaS)

About MoBaS

MoBaS is a software tool for finding the disease associated subnetworks in protein-protein interaction (PPI) networks. A disease associated subnetwork is a subset of gene products that are heavily connected to each other in the protein-protein interaction network and are significantly associated with the disease when considered together.

MoBaS uses a scoring method that is parameter-free and aims to score subnetworks by assessing the disease association of pairwise interactions and incorporating the statistical significance of network connectivity and disease association.

MoBaS is implemented in Java. It can be downloaded in the form of a jar file or as source code.